Appendix A1.

Dosing tables for omalizumab administered by subcutaneous injection every 4 weeks (A) or every 2 weeks (B)

	Bodyweight (kg)
Baseline IgE (IU/mL)	>20–30	>30–40	>40–50	>50–60	>60–70	>70–80	>80–90	>90–125	>125–150
A
≥30–100	150	150	150	150	150	150	150	300	300
>100–200	150	150	300	300	300	300	300
>200–300	150	300	300	300
>300–400	300	300
>400–500	300						Administration every 2 weeks see Part B
>500–600	300
B
≥30–100		Administration every 4 weeks see Part A
>100–200								225	300
>200–300					225	225	225	300	375
>300–400			225	225	225	300	300
>400–500		225	225	300	300	375	375
>500–600		225	300	300	375
>600–700	225	225	300	375
>700–800	225	300	375
>800–900	225	300	375
>900–1000	300	375				DO NOT DOSE
>1000–1100	300	375
>1100–1200	300
>1200–1300	375

Omalizumab doses are given in mg/dose.

These dosing tables differ from the dosing tables provided in the package inserts of the marketed product.