Table 3.2.3 Incidence and prevalence rates (per 100 000 population) for Crohn's disease and for ulcerative colitis, as reported from various regional studies in the UK.
| City/region | Study period | Study sources* | No of cases | Incidence rate per 100 000 population | Prevalence per 100 000 population | Authors and reference |
|---|---|---|---|---|---|---|
| Crohn's disease: | ||||||
| Cardiff | 1931–90 | SP, HR, Lab | 86 | 2.3 in 1961–65 11.9 in 1981–85 8.6 in 1986–90 | – | Thomas GA et al, 1995121 |
| Cardiff | 1991–95 | SP, HR, Lab | 84 | 5.6 | – | Yapp TR et al, 2000122 |
| Oxford | 1951–60 | SP, HR | 24 | 0.8 | 9 in 1960 | Evans JG and Acheson ED, 1965131 |
| Derby | 1951–85 | HR, Lab | 225 | 0.7 in 1951–55 6.7 in 1981–85 | 85 in 1985 | Fellows IW et al, 1990124 |
| Nottingham | 1958–72 | SP, HR, Lab | 144 | 0.7 in 1958–60 3.6 in 1970–72 | – | Miller DS et al, 1974137 |
| Clydesdale | 1961–70 | HR | 357 | 1.2 in 1961–65 1.9 in 1966–70 | – | Smith IS et al, 1975138 |
| Gloucester | 1966–70 | HR, Lab | 19 | 1.5 | – | Tresadern JC et al, 1973139 |
| North Tees | 1971–77 | HR, Lab | 73 | 5.3 | 35 in 1977 | Devlin HB et al, 1980134 |
| NE Scotland and N Isles of Scotland | 1955–88 | SP, HR, Lab | 1008 | 1.3 in 1955–57 9.8 in 1985–87 | 147 in 1988 | Kyle J, 1992123 |
| Northern Ireland | 1966–81 | HR, Lab | 440 | 1.3 in 1966–73 2.3 in 1974–81 | – | Humphreys WG et al, 1990140 |
| Blackpool | 1968–80 | HR, Lab | 156 | 3.3 in 1971–75 6.1 in 1976–80 | 47 in 1980 | Lee FI and Costello FT, 1985125 |
| Leicestershire | 1972–89 | SP, HR, Lab | 582 | 3.2–4.7 (among Europeans) | – | Jayanthi V et al, 1992126 |
| North Tees | 1985–94 | SP | 200 | 8.3 | 145 in 1994 | Rubin GP et al, 2000136 |
| Trent | 2002 | SP, HR, Lab | 113 | – | 130 in 2002 | Stone MA et al, 2003141 |
| Ulcerative colitis: | ||||||
| Oxford | 1951–60 | SP, HR | 238 | 6.5 | 80 in 1960 | Evans JG and Acheson ED, 1965131 |
| NE Scotland | 1967–76 | SP, HR, Lab | 537 | 11.3 | – | Sinclair TS et al, 1983135 |
| Cardiff | 1968–87 | SP, HR, Lab | 6.4 in 1968–77 6.3 in 1978–87 | – | Srivastava ED et al, 1992133 | |
| North Tees | 1971–77 | HR, Lab | 146 | 15.1 | 99 in 1977 | Devlin HB et al, 1980134 |
| High Wycombe | 1975–84 | HR, Lab | 313 | 7.1 | 84 in 1984 | Jones HW et al, 1988132 |
| North Tees | 1985–94 | SP | 334 | 13.9 | 243 in 1994 | Rubin GP et al, 2000136 |
| Trent | 2002 | SP, HR, Lab | 211 | – | 243 in 2002 | Stone MA et al, 2003141 |
*Study sources: SP, survey of physicians; HR, review of hospital records or admission data; Lab, pathology data.