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. 2006 Sep;55(9):1248–1254. doi: 10.1136/gut.2005.079350

Table 2 Clinical characteristics of 18 patients with a cause of death related to Crohn's disease: a population based study, Olmsted County, Minnesota, 1940–2004.

Cause of death Sex Maximal extent of CD Calendar year at diagnosis Age at diagnosis (y) Age at death (y) Disease duration (y)
Complications of Crohn's disease
Severe disease, fistulas, perforation, sepsis
1 Intra‐abdominal abscess, peritonitis F Colonic 1972 53 53 <1
2 Sepsis after surgery for internal fistula, recent infliximab treatment F Ileocolonic 1990 25 35 10
3 Severe CD, sepsis M Colonic 1943 56 56 <1
4 Severe CD, ileum perforation, peritonitis M Ileocolonic 1949 56 62 6
5 Severe fistulising CD, sepsis M Colonic 1965 77 77 <1
6 Severe fistulising CD, peritonitis, MI M Ileocolonic 1973 47 48 1
Short bowel syndrome
7 Short bowel syndrome after surgery for internal fistulas, COPD F Ileocolonic 1976 52 71 19
8 Short bowel syndrome, intestinal ischemia M Ileocolonic 1962 42 61 19
PSC and cholagiocarcinoma
9 End stage liver disease due to PSC F Ileocolonic 1980 35 46 11
10 End stage liver disease due to PSC M Colonic 1987 39 49 10
11 Cholangiocarcinoma of hepatic bile ducts and hemorrhagic pancreatitis M Ileocolonic 1954 30 62 32
Embolism
12 Steroid refractory CD, pulmonary embolism F Ileocolonic 1972 43 57 14
Median (range) 43 (15–77) 56 (17–77) 11 (1–32)
Intestinal cancer
1 Metastatic leiomyosarcoma of small bowel F Ileocolonic 1951 32 63 31
2 Metastatic ileocaecal adenocarcinoma F Ileocolonic 1978 25 34 9
3 Metastatic colorectal cancer F Colonic 1969 30 43 13
4 Small bowel lymphoma M Jejunal, ileocolonic 1967 23 47 24
5 Metastatic colorectal cancer M Jejunum, ileocolonic 1962 13 30 17
6 Metastatic colorectal cancer M Ileal 1987 69 70 1
Median (range) 28 (13–69) 45 (30–70) 15 (1–31)

CD, Crohn's disease; COPD, chronic obstructive pulmonary disease; PSC, primary sclerosing cholangitis; F, female; M, male; MI, acute myocardial infarction.