Table 2 Clinical characteristics of 18 patients with a cause of death related to Crohn's disease: a population based study, Olmsted County, Minnesota, 1940–2004.
Cause of death | Sex | Maximal extent of CD | Calendar year at diagnosis | Age at diagnosis (y) | Age at death (y) | Disease duration (y) | |
---|---|---|---|---|---|---|---|
Complications of Crohn's disease | |||||||
Severe disease, fistulas, perforation, sepsis | |||||||
1 | Intra‐abdominal abscess, peritonitis | F | Colonic | 1972 | 53 | 53 | <1 |
2 | Sepsis after surgery for internal fistula, recent infliximab treatment | F | Ileocolonic | 1990 | 25 | 35 | 10 |
3 | Severe CD, sepsis | M | Colonic | 1943 | 56 | 56 | <1 |
4 | Severe CD, ileum perforation, peritonitis | M | Ileocolonic | 1949 | 56 | 62 | 6 |
5 | Severe fistulising CD, sepsis | M | Colonic | 1965 | 77 | 77 | <1 |
6 | Severe fistulising CD, peritonitis, MI | M | Ileocolonic | 1973 | 47 | 48 | 1 |
Short bowel syndrome | |||||||
7 | Short bowel syndrome after surgery for internal fistulas, COPD | F | Ileocolonic | 1976 | 52 | 71 | 19 |
8 | Short bowel syndrome, intestinal ischemia | M | Ileocolonic | 1962 | 42 | 61 | 19 |
PSC and cholagiocarcinoma | |||||||
9 | End stage liver disease due to PSC | F | Ileocolonic | 1980 | 35 | 46 | 11 |
10 | End stage liver disease due to PSC | M | Colonic | 1987 | 39 | 49 | 10 |
11 | Cholangiocarcinoma of hepatic bile ducts and hemorrhagic pancreatitis | M | Ileocolonic | 1954 | 30 | 62 | 32 |
Embolism | |||||||
12 | Steroid refractory CD, pulmonary embolism | F | Ileocolonic | 1972 | 43 | 57 | 14 |
Median (range) | 43 (15–77) | 56 (17–77) | 11 (1–32) | ||||
Intestinal cancer | |||||||
1 | Metastatic leiomyosarcoma of small bowel | F | Ileocolonic | 1951 | 32 | 63 | 31 |
2 | Metastatic ileocaecal adenocarcinoma | F | Ileocolonic | 1978 | 25 | 34 | 9 |
3 | Metastatic colorectal cancer | F | Colonic | 1969 | 30 | 43 | 13 |
4 | Small bowel lymphoma | M | Jejunal, ileocolonic | 1967 | 23 | 47 | 24 |
5 | Metastatic colorectal cancer | M | Jejunum, ileocolonic | 1962 | 13 | 30 | 17 |
6 | Metastatic colorectal cancer | M | Ileal | 1987 | 69 | 70 | 1 |
Median (range) | 28 (13–69) | 45 (30–70) | 15 (1–31) |
CD, Crohn's disease; COPD, chronic obstructive pulmonary disease; PSC, primary sclerosing cholangitis; F, female; M, male; MI, acute myocardial infarction.