Figure 7 (A) Dose dependent in vivo effects of intravenous application of the Rho‐kinase inhibitor Y‐27632 on portal pressure in sham operated (sham) and bile duct ligated (BDL) rats, determined 45 minutes after bolus injection. (B) Dose dependent in vivo effects of intravenous application of the Rho‐kinase inhibitor Y‐27632 (0.1 and 1 mg/kg bw) on mean arterial pressure in sham operated and BDL rats, determined 45 minutes after bolus injection. Data are means with SEM, n = 11–27 in each group. (C) Dose dependent in vivo effects of intravenous application of the Rho‐kinase inhibitor Y‐27632 (0.1 and 1 mg/kg bw) on splanchnic vascular resistance in sham operated and BDL rats, determined 45 minutes after bolus injection. (D) Dose dependent in vivo effects of intravenous application of the Rho‐kinase inhibitor Y‐27632 (0.1 and 1 mg/kg bw) on hepatic arterial flow in sham operated and BDL rats, determined 45 minutes after bolus injection. Data are means with SEM, n = 11–27 in each group. bw, body weight.