Table 1.
Reefman et al. [1] | Kuhn et al. [11] | Jannsens et al. [12] | |
Patients | SLE | DLE, SCLE, TLE | DLE, SCLE, SLE |
Photosensitive | 6/15 | All | All |
Treatment | Steroids, azathioprine | No steroids | 3/22 steroids |
Controls | Healthy | SLE, healthy | Healthy |
UV | UVB, 2MEDs | UVA or UVB, 1.5 MED | UVB, 6 MEDs |
Site | Buttock | Upper back | Buttock |
Frequency | Once | Three times | Once |
Apoptosis detection | Sunburn cells, casp3 | ISNT, TUNEL, casp3 | Casp3 |
Time analyzed (days) | 3, 10 | 1, 3 and up to 28 | 1, 2, 3 |
Casp3, activated caspase 3; DLE, discoid lupus erythematosus; ISNT, in situ nick translation; MED, minimal erythemal dose; SCLE, subacute cutaneous lupus erythematosus; SLE, systemic lupus erythematosus; TLE, tumid lupus erythematosus; TUNEL, in situ nick end labeling.