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. 2006 Nov;55(11):1650–1660. doi: 10.1136/gut.2006.091454

Table 3 Panel marker tests measuring fibrosis in non‐alcoholic fatty liver disease.

Test Components of panel Fibrosis stage Training or validation n AUC Cut off SENS SPEC PPV NPV
HA score Age >45, obesity, AST/ALT ratio >1, diabetes, HA F3/4 v F0/1/2 Training 79 0.92 CI (0.85–0.98) N/S N/S N/S N/S N/S
ELF score Age, HA, TIMP‐1, PIIINP F3/4 v F0/1/2 Validation 61 0.87 CI (0.66–1) 0.37 89 96 80 98
0.46 78 98 87 96
BAAT score Age, BMI, ALT, serum triglycerides F2/3/4 v F0/1 Training 93 0.84 CI (N/S) 0 100 11 33 100
1 100 47 45 100
2 71 80 61 86
3 14 100 100 73
4 0 100 0 70

AST, aspartate aminotransferase; ALT, alanine aminotransferase; HA, hyaluronic acid; TIMP‐1, tissue inhibitor of metalloproteinase; PIIINP, aminoterminal peptide of procollagen III; BMI, body mass index; AUC, area under the curve; CI, confidence interval; N/S, not stated; SENS, sensitivity; SPEC, specificity; PPV, positive predictive value; NPV, negative predictive value.