Table 1 Plasma levels of bilirubin, nitrate+nitrite, alkaline phosphatase activity (ALP), and alanine transaminase activity (ALT) in control (CTR) and bile duct ligated (BDL) rats given naltrexone or saline.
| CTR | BDL | |||
|---|---|---|---|---|
| Saline | Naltrexone | Saline | Naltrexone | |
| Plasma bilirubin(mg/dl) | 0.47 (0.05) | 0.44 (0.06) | 13.45 (1.65)*** | 11.42 (1.07)*** |
| Plasma ALP activity (U/l) | 376 (36) | 300 (39) | 917 (45)*** | 701 (32)†† |
| Plasma ALT activity (U/l) | 38.4 (2.9) | 40.1 (3.5) | 100.6 (9.5)*** | 63.7 (8.6)‡ |
| Plasma nitrite+nitrate (μM) | 15.2 (2.1) | 13.5 (3.1) | 21.7 (1.9) | 22.1 (4.7) |
***p<0.001 compared with control groups; ††p<0.01 compared with BDL/saline group; ‡p<0.05 compared with BDL/saline group.