Table 2 Results of time dependent covariate analysis assessing the effect on survival of age, initial neurokinin A (NKA) concentration, and most recent NKA concentration (both log transformed and with hazard ratios scaled to represent a doubling in value).

	Hazard ratio (95% CI)	p Value
Age (per decade)	1.77 (1.10, 2.86)	0.02
Initial NKA (per doubling)	1.15 (0.85, 1.55)	0.35
Most recent NKA (per doubling)	1.49 (1.12, 1.97)	0.006

95% CI, 95% confidence interval.