Table 2 Cox regression models for possible factors influencing the probability of developing avascular areas after MMC augmented glaucoma surgery and for TCO and bleb leaks to develop in eyes with avascular blebs.
| Risk factor | Model 1 bleb avascularity | Model 2 TCO in avascular blebs | Model 3 leaks in avascular blebs | |||
|---|---|---|---|---|---|---|
| Hazard ratios (95% CI) | p Value | Hazard ratios (95% CI)) | Hazard ratios (95% CI) | p Value | ||
| Age | 1.00 (0.98 to 1.02) | 0.77 | 1.00 (0.97 to 1.03) | 0.78 | 0.99 (0.93 to 1.07) | 0.94 |
| Sex | 1.04 (0.82 to 1.33) | 0.69 | 1.11 (0.84 to 1.47) | 0.45 | 1.00 (0.51 to 1.97) | 0.99 |
| Surgeon | 1.22 (0.69 to 2.16) | 0.49 | 0.74 (0.41 to 1.13) | 0.31 | 0.96 (0.19 to 4.83) | 0.97 |
| Type of procedure | 0.58 (0.34 to 0.99) | 0.05 | 0.61 (0.35 to 1.07) | 0.08 | 0.06 (0.01 to 0.31) | 0.0007 |
| Combined procedure | 0.60 (0.33 to 1.08) | 0.09 | 0.82 (0.45 to 1.51) | 0.53 | 1.19 to (0.31 to 3.93) | 0.80 |
| MMC application >2 minutes | 1.23 (0.54 to 2.81) | 0.62 | 0.59 (0.25 to 1.40) | 0.23 | 0.83 (0.19 to 3.66) | 0.81 |
| Previous intraocular surgery | 0.75 (0.35 to 1.60) | 0.45 | 0.64 (0.29 to 1.40) | 0.27 | 0.64 (0.14 to 2.89) | 0.57 |
| More than one previous ocular surgery | 0.66 (0.22 to 1.93) | 0.21 | 2.54 (0.73 to 8.80) | 0.14 | 2.02 (0.30 to 13.7) | 0.47 |
| Subconjunctival 5‐FU | 0.32 (0.11 to 0.91) | 0.03 | 0.96 (0.21 to 4.35) | 0.96 | No convergence | |
| Needle revision with 5‐FU within 3 months of surgery | 0.78 (0.24 to 2.57) | 0.69 | 0.76 (0.15 to 3.82) | 0.74 | No convergence | |
| Avascular area more than 4 mm | 3.77 (1.66 to 8.56) | 0.001 | No convergence | |||