Table 4 Microscopic features that distinguish MPC from MF.
Feature | MPC | MF |
---|---|---|
HPC‐like vascular spaces* | ++ | + |
Concentric perivascular proliferation | +++ | + |
Zonation/biphasic appearance† | + | +++ |
Glomus‐like cells‡ | + to +++ | − |
Hyalinised paucicellular areas | + | +++ |
Myoid‐like cells§ | + | ++ |
Primitive cells¶ | + | ++ |
Bulging or intravascular proliferation | + | ++ |
Myoid nodules | −/+ | ++ |
Necrosis | − | + |
*Numerous lesional blood vessels that are variable in size, ectatic, with thin walls and a branching “staghorn” arrangement; †architectural arrangement of myoid‐like cells and primitive cells in separate areas, usually the myoid cells peripherally and the primitive cells centrally; ‡cuboidal shaped cells, with distinct cell borders, clear to eosinophilic cytoplasm, and central round nuclei; §oval/spindle shaped cells with eosinophilic cytoplasm; ¶round/polygonal cells with a small amount amphophilic cytoplasm and indistinct cell borders, typically surrounding blood vessels in HPC‐like areas.
HPC, haemangiopericytoma; MF, myofibroma; MPC, myopericytoma.