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| Factors | Lymph node metastasis | ||
|---|---|---|---|
| Negative | Positive | p Value | |
| LVI‐HE | |||
| Negative | 70 | 18 | <0.001 |
| Positive | 3 | 26 | |
| LVI‐IHC | <0.001 | ||
| Negative | 59 | 16 | |
| Positive | 14 | 28 | |
LVD, podoplanin positive lymph vessel density; LVI‐HE, lymph vessel invasion detected by haematoxylin and eosin staining; LVI‐IHC, lymph vessel invasion detected by podoplanin immunohistochemistry.
