Table 1 Comparison of acute and chronic changes in 23 renal allograft biopsies containing both cortex and medulla.
| Change* | Cortex (n = 23) | Medulla (n = 23) | p Value |
|---|---|---|---|
| I | 1.0 (0.5) | 0.4 (0.5) | <0.001† |
| T | 1.2 (0.7) | 0.2 (0.5) | <0.001† |
| V | 0.26 (0.6) | – | |
| G | 0.3 (0.5) | – | |
| CT | 1.17 (0.7) | 0.48 (0.7) | 0.002† |
| CI | 1.17 (0.7) | – | |
| CV | 0.78 (0.8) | – | |
| AH | 0.55 (0.9) | – | |
| CG | 0.2 (0.5) | – | |
| SAP | 12.7 (5.9) (PAMS) | 19.2 (10.6) (MT) | 0.02‡ |
Values are mean (SD).
*Based on the Banff classification for renal allograft pathology.5
†Mann–Whitney U test.
‡Linear regression test.
AH, arteriolar hyaline thickening; CG, allograft glomerulopathy; CI, interstitial fibrosis; CT, tubular atrophy; CV, vascular fibrous intimal thickening; G, glomerulitis; I, interstitial inflammation; SAP, stained area percentage obtained by computed image analysis using PAMS (periodic acid‐methenamine silver) or MT (Masson trichrome staining); T, tubulitis; V, vasculitis.