Table 2 Sensitivity and specificity of renal medullary changes for acute renal allograft rejection in 23 biopsies containing both cortex and medulla.
| Cortex (n = 23) | Medulla (n = 23) | |
|---|---|---|
| Tubulitis | Interstitial inflammation | |
| Acute rejection (n = 7) | 0.3 (0.7) | 0.43 (0.53) |
| Borderline changes (n = 12) | 0.25 (0.45) | 0.5 (0.67) |
| No evidence of rejection (n = 4) | 0 | 0 |
| Tubulitis in medulla | Interstitial inflammation in medulla | |
|---|---|---|
| Sensitivity | 14% | 43% |
| Specificity | 81% | 69% |
| Positive predictive value | 25% | 37% |
| Negative predictive value | 68% | 73% |