Table 4 Univariate survival analysis (Kaplan–Meier): overall and disease‐free survival times of all patients with breast cancer according to clinicopathological factors and ALCAM expression.
| Characteristic | Overall survival | Disease‐free survival | ||||||
|---|---|---|---|---|---|---|---|---|
| No of cases | No of events | 5 year survival (SE) | p Value | No of cases | No of events | 5 year non‐progression (SE) | p Value | |
| Membranous ALCAM expression | 0.031 | 0.779 | ||||||
| Low | 126 | 17 | 88.4 (3.2) | 126 | 40 | 65.9 (5.0) | ||
| High | 36 | 10 | 76.4 (8.0) | 36 | 11 | 66.0 (8.9) | ||
| Cytoplasmic ALCAM expression | 0.067 | 0.014 | ||||||
| Low | 134 | 20 | 88.9 (3.1) | 134 | 38 | 69.4 (4.6) | ||
| High | 28 | 7 | 68.4 (10.1) | 28 | 13 | 49.4 (11.1) | ||
| Age | 0.945 | 0.437 | ||||||
| <60 years | 86 | 14 | 89.1 (3.7) | 86 | 29 | 59.2 (6.4) | ||
| ⩾60 years | 76 | 13 | 82.1 (5.0) | 76 | 22 | 73.8 (5.3) | ||
| Histology | 0.552 | 0.264 | ||||||
| Ductal | 144 | 25 | 84.8 (3.4) | 144 | 48 | 65.1 (4.6) | ||
| Lobular | 18 | 2 | 92.9 (6.9) | 18 | 3 | 73.9 (13.1) | ||
| pT stage | 0.0005 | 0.0005 | ||||||
| pT1 | 103 | 7 | 94.1 (2.6) | 103 | 24 | 78.5 (4.6) | ||
| pT2 | 44 | 14 | 74.0 (7.6) | 44 | 22 | 34.8 (9.4) | ||
| PT3/4 | 15 | 6 | 63.0 (13.3) | 15 | 5 | 63.0 (13.3) | ||
| Nodal status | 0.0064 | 0.0018 | ||||||
| pN0 | 79 | 5 | 93.6 (3.1) | 79 | 15 | 80.5 (5.2) | ||
| pN1+ | 81 | 22 | 77.9 (5.1) | 81 | 34 | 53.7 (6.5) | ||
| UICC stage | 0.0078 | 0.0064 | ||||||
| I | 80 | 5 | 93.7 (3.1) | 80 | 16 | 79.4 (5.2) | ||
| II | 56 | 13 | 84.0 (5.6) | 56 | 25 | 47.8 (8.2) | ||
| III | 26 | 9 | 65.9 (10.0) | 26 | 10 | 61.5 (10.2) | ||
| Histological grade | 0.0114 | 0.0029 | ||||||
| G1 | 40 | 3 | 92.0 (5.4) | 40 | 5 | 84.2 (6.6) | ||
| G2 | 82 | 11 | 89.6 (3.8) | 82 | 28 | 67.0 (5.9) | ||
| G3 | 40 | 13 | 71.4 (7.8) | 40 | 18 | 43.9 (10.4) | ||
| Oestrogen receptor | 0.1639 | 0.1155 | ||||||
| Negative | 42 | 11 | 79.6 (6.5) | 42 | 17 | 59.6 (8.3) | ||
| Positive | 106 | 14 | 87.5 (3.8) | 106 | 29 | 70.4 (5.3) | ||
| c‐erbB2 expression | 0.4172 | 0.4059 | ||||||
| 0, 1+ | 100 | 16 | 86.8 (3.8) | 100 | 29 | 71.3 (5.5) | ||
| 2+, 3+ | 35 | 6 | 81.9 (7.4) | 35 | 12 | 59.27 (9.2) | ||
ALCAM, activated leucocyte cell adhesion molecule; pT, primary tumour; UICC, International Union Against Cancer.