Table 2 Pearson correlations between different markers of GFR.
*Plasma creatinine | Cystatin C | *β2‐microglobulin | *Cockcroft‐Gault GFR | MDRD GFR | *Calculated CC clearance | Measured Ccr | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
(μmol/l) | (mg/l) | (mg/l) | (ml/min) | (ml/min/1.73 m2) | (ml/min/1.73 m2) | (ml/min) | ||||||
(A) Uncorrected | ||||||||||||
Plasma creatinine (µmol/l) | r | |||||||||||
p | ||||||||||||
Cystatin C (mg/l) | r | 0.050 | ||||||||||
p | 0.732 | |||||||||||
β2‐Microglobulin (mg/l) | r | 0.331 | 0.677 | |||||||||
p | 0.028 | <0.0001 | ||||||||||
Cockcroft‐Gault GFR | r | −0.699 | −0.107 | −0.269 | ||||||||
(ml/min) | p | <0.0001 | 0.475 | 0.081 | ||||||||
MDRD GFR | r | −0.802 | −0.182 | −0.348 | 0.783 | |||||||
(ml/min/1.73 m2) | p | <0.0001 | 0.217 | 0.021 | <0.0001 | |||||||
Calculated CC clearance | r | −0.239 | −0.663 | −0.469 | 0.117 | 0.276 | ||||||
(ml/min/1.73 m2) | p | 0.167 | <0.0001 | 0.004 | 0.517 | 0.115 | ||||||
Measured Ccr (ml/min) | r | −0.207 | −0.150 | −0.033 | 0.434 | 0.271 | 0.271 | |||||
p | 0.256 | 0.413 | 0.864 | 0.015 | 0.134 | 0.222 | ||||||
(B) After correction for sex | ||||||||||||
Plasma creatinine (μmol/l) | r | |||||||||||
p | ||||||||||||
Cystatin C (mg/l) | r | 0.044 | ||||||||||
p | 0.767 | |||||||||||
β2‐Microglobulin (mg/l) | r | 0.339 | 0.677 | |||||||||
p | 0.026 | <0.0001 | ||||||||||
Cockcroft‐Gault GFR | r | −0.739 | −0.106 | |||||||||
(ml/min) | p | <0.0001 | 0.482 | 0.086 | ||||||||
MDRD GFR | r | −0.803 | −0.180 | −0.346 | 0.791 | |||||||
(ml/min/1.73 m2) | p | <0.0001 | 0.226 | 0.023 | <0.0001 | |||||||
Calculated CC clearance | r | −0.147 | −0.687 | −0.480 | 0.115 | 0.236 | ||||||
(ml/min/1.73 m2) | p | 0.408 | <0.0001 | 0.004 | 0.532 | 0.186 | ||||||
Measured Ccr (ml/min) | r | −0.272 | −0.154 | −0.039 | 0.441 | 0.301 | 0.328 | |||||
p | 0.138 | 0.407 | 0.845 | 0.015 | 0.100 | 0.147 |
*Log transformed before analysis.
CC, cystatin C; Ccr, creatinine clearance; GFR, glomerular filtration rate; MDRD, modified Modification of Diet in Renal Disease.