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. 2006 Apr;59(4):345–351. doi: 10.1136/jcp.2005.026799

Table 2 Pearson correlations between different markers of GFR.

*Plasma creatinine Cystatin C 2‐microglobulin *Cockcroft‐Gault GFR MDRD GFR *Calculated CC clearance Measured Ccr
(μmol/l) (mg/l) (mg/l) (ml/min) (ml/min/1.73 m2) (ml/min/1.73 m2) (ml/min)
(A) Uncorrected
Plasma creatinine (µmol/l) r
p
Cystatin C (mg/l) r 0.050
p 0.732
β2‐Microglobulin (mg/l) r 0.331 0.677
p 0.028 <0.0001
Cockcroft‐Gault GFR r −0.699 −0.107 −0.269
(ml/min) p <0.0001 0.475 0.081
MDRD GFR r −0.802 −0.182 −0.348 0.783
(ml/min/1.73 m2) p <0.0001 0.217 0.021 <0.0001
Calculated CC clearance r −0.239 −0.663 −0.469 0.117 0.276
(ml/min/1.73 m2) p 0.167 <0.0001 0.004 0.517 0.115
Measured Ccr (ml/min) r −0.207 −0.150 −0.033 0.434 0.271 0.271
p 0.256 0.413 0.864 0.015 0.134 0.222
(B) After correction for sex
Plasma creatinine (μmol/l) r
p
Cystatin C (mg/l) r 0.044
p 0.767
β2‐Microglobulin (mg/l) r 0.339 0.677
p 0.026 <0.0001
Cockcroft‐Gault GFR r −0.739 −0.106
(ml/min) p <0.0001 0.482 0.086
MDRD GFR r −0.803 −0.180 −0.346 0.791
(ml/min/1.73 m2) p <0.0001 0.226 0.023 <0.0001
Calculated CC clearance r −0.147 −0.687 −0.480 0.115 0.236
(ml/min/1.73 m2) p 0.408 <0.0001 0.004 0.532 0.186
Measured Ccr (ml/min) r −0.272 −0.154 −0.039 0.441 0.301 0.328
p 0.138 0.407 0.845 0.015 0.100 0.147

*Log transformed before analysis.

CC, cystatin C; Ccr, creatinine clearance; GFR, glomerular filtration rate; MDRD, modified Modification of Diet in Renal Disease.