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. 2006 Feb 23;59(7):685–691. doi: 10.1136/jcp.2005.030650

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Figure 3 Box plots showing the relationship between cyclo‐oxygenase‐2 (COX‐2) immunoexpression and the percentage of phospho‐Akt (pAkt; serine 473 and threonine 308) positively stained tumour nuclei. Tumours with or without COX‐2 expression exhibited equal amounts of pAkt tumour cells independent of the phosphorylation site. Open circles indicate outliers; asterisks indicate extreme values. Data were available for 95 cases (pAkt threonine 308) and for 113 cases (pAkt serine 473).