Table 3 Multivariate Cox regression analysis of disease‐specific overall survival in 113 cases of node‐negative breast cancers.

Variable*	Relative risk	95% CI	p Value
COX‐2	3.509	1.099 to 11.208	0.034†
Grading	5.537	1.244 to 24.532	0.025†
pAkt (473)	3.976	0.861 to 18.366	0.077
Mitotic count	0.774	0.278 to 2.156	0.624

COX, cyclo‐oxygenase; pAkt, phospho‐Akt.

*Coding of variables: pAkt was coded as 1, negative; and 2, positive. COX‐2 was coded as 1, negative; and 2, positive. Mitotic count was coded as 1, 0–18; 2, 9–16; and 3, >16.

†Significant.