Table 1 Clinical, histological and immunohistochemical findings in three patients with gastric plasma cell crystals.
Age, sex | Symptoms/endoscopy | Gastric biopsy findings | PCC | IHC in PCC | Other findings | Follow‐up | |
---|---|---|---|---|---|---|---|
Case 1 | 82, M | Dyspepsia, antral gastritis | Moderate acute and chronic gastritis. HP present | Focal, up to 32/HPF | IgA λ | No PCC in duodenal, colonic or rectal biopsies No paraprotein on serum electrophoresis | Died of unrelated causes 4 months after biopsy |
Case 2 | 81, M | Dysphagia, oesophagitis | Mild acute and chronic gastritis. HP present | Focal, up to 2/HPF | Insufficient PCC for assessment | No PCC in duodenal, ileal or rectal biopsies | No gastric symptoms 14 months after biopsy |
Case 3 | 52, F | Diarrhoea, oesophagitis, antral erosion | Moderate acute and chronic gastritis. HP present | Focal, up to 5/HPF | IgA λ | No PCC in oesophageal biopsies | No gastric symptoms 6 months after biopsy History of hypertension and hypothyroidism |
F, female; HP, Lelicobacter pylori; HPF, high‐power field (×400 magnification); IgA, immunoglobulin A; IHC, immunohistochemistry; M, male; PCC, plasma cells with crystals.