Table 3 Association between gene methylation and demographic characteristics.
| p15 | p | p16 | p | p57 | p | ||||
|---|---|---|---|---|---|---|---|---|---|
| Unmethylated | Methylated | Unmethylated | Methylated | Unmethylated | Methylated | ||||
| Median age | 63.5 | 68.5 | 0.19 | 64.5 | 65.5 | 0.72 | 64.5 | 67.5 | 0.47 |
| Median lymphocyte count | 17.0 | 21.5 | 0.25 | 16.0 | 64.5 | 0.016 | 16.0 | 31.5 | 0.17 |
| Sex | |||||||||
| Men | 30 | 14 | 0.31 | 38 | 6 | 0.99 | 41 | 3 | 0.99 |
| Women | 6 | 6 | 10 | 2 | 11 | 1 | |||
| Rai stage | |||||||||
| ⩽2 | 21 | 10 | 0.77 | 27 | 5 | 0.99 | 30 | 2 | 0.99 |
| >2 | 13 | 9 | 19 | 3 | 20 | 2 | |||
| Poor‐risk karyotype | |||||||||
| Yes | 15 | 8 | 0.74 | 21 | 2 | 0.63 | 21 | 2 | 0.50 |
| No | 9 | 7 | 13 | 3 | 16 | 0 | |||
Association between gene methylation and age and lymphocyte count was analysed by the Mann–Whitney test, and association with sex, Rai stage and presence of poor‐risk karyotype was analysed by the χ2 or Fisher's exact test.