Table 2 Immunophenotypic profile of the immune cells in the normal breast, benign proliferative breast disease, ductal carcinoma in situ and infiltrating ductal carcinoma in both parenchyma and stroma.
CD3+ | CD20+ | CD68+ | Granzyme B+ | |||||
---|---|---|---|---|---|---|---|---|
Parenchyma | Stroma | Parenchyma | Stroma | Parenchyma | Stroma | Parenchyma | Stroma | |
Normal | 2.8 (1.0) | 1.4 (0.6) | 3.2 (1.0) | 0.7 (0.3) | 1.3 (0.7) | 1.0 (0.6) | 0.5 (0.3) | 0.0 (0.0) |
Benign proliferative breast disease | 81.5 (14.0) | 4.2 (1.2) | 26.4 (7.8) | 3.0 (1.2) | 3.8 (1.2) | 4.0 (0.6) | 2.3 (1.4) | 0.5 (0.3) |
Ductal carcinoma in situ | 84.0 (14.9) | 46.6 (16.7) | 33.6 (7.9) | 13.3 (6.7) | 12.7 (3.7) | 16.7 (1.7) | 8.5 (6.9) | 0.7 (0.3) |
Infiltrating ductal carcinoma | 103.7 (3.9) | 77.0 (5.0) | 39.1 (4.7) | 16.7 (8.8) | 22.1 (4.1) | 21.7 (4.4) | 16.3 (4.9) | 0.7 (0.3) |
Values are mean (standard error of mean).