Figure 4 Time‐course changes of pSmad2 localisation in bleomycin‐induced pulmonary fibrosis. Representative immunohistochemical results for pSmad2 for the bleomycin‐treated group on day 9 (A,B). (A) Arrowheads indicate pSmad2‐positive signals on macrophages. Note the intense pSmad2‐positive signals observed in the nucleus of infiltrating macrophages. (B) Arrows indicate pSmad2‐positive signals on fibroblasts. Note that faintly pSmad2‐positive signals were observed in the nucleus of fibroblasts in fibroblastic foci.