Table 2 Focal manifestations of infection, age dependence and involved bacterial groups.
| Age (years) | <2 | 2–<4 | 4–<15 | 15–<25 | ⩾25 | |||
|---|---|---|---|---|---|---|---|---|
| Number of patients | 10 | 20 | 20 | 10 | 10 | |||
| Tissue | T | A | T | A | T | A | T | T |
| Number of samples | 10 | 10 | 20 | 20 | 20 | 10 | 10 | 10 |
| No signs of infection | 1 | 1 | 2 | 5 | 4 | 8 | 1 | 4 |
| Adherent infiltrates | ||||||||
| No adherence (single bacteria irregularly attached to the epithelium) | 5 | 8 | 12 | 16 | 4 | 9 | 1 | 5 |
| Adherence exclusively to crypt entrance and within crypts | 0 | 0 | 0 | 0 | 1 | 1 | 2 | 4 |
| Islands of adherence covering <5% of the epithelial surface | 4 | 2 | 6 | 4 | 10 | 4 | 4 | 1 |
| Lawns of bacteria covering >5% of the epithelial surface | 1 | 0 | 2 | 0 | 5 | 1 | 3 | 0 |
| Fissures | ||||||||
| No fissures | 5 | 7 | 8 | 15 | 5 | 7 | 7 | 10 |
| 1–3 | 4 | 1 | 10 | 5 | 6 | 7 | 3 | 0 |
| >3 | 1 | 2 | 2 | 0 | 5 | 0 | 0 | 0 |
| Branched fissures | 0 | 0 | 0 | 0 | 4 | 1 | 0 | 0 |
| Abscesses | 1 | 0 | 4 | 1 | 7 | 2 | 0 | 0 |
| Diffuse infiltration of tissue | 7 | 6 | 12 | 7 | 6 | 3 | 0 | 0 |
| Occurrence of bacterial groups | ||||||||
| Haemophilus influenzae (Haeinf) | 7 | 6 | 14 | 6 | 9 | 2 | 2 | 0 |
| Beta‐Proteobacteria incl. Neisseria (Bet42a) | 2 | 0 | 2 | 0 | 3 | 0 | 1 | 2 |
| Actinobacteria (HGC) | 6 | 5 | 9 | 3 | 6 | 4 | 0 | 2 |
| Atopobium and other (Ato291) | 0 | 0 | 1 | 0 | 2 | 0 | 1 | 0 |
| Coriobacterium group (Cor653) | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 1 |
| Firmicutes (LGC) | 3 | 3 | 11 | 8 | 13 | 7 | 4 | 3 |
| Fusobacteria (Fuso) | 0 | 0 | 5 | 2 | 4 | 1 | 1 | 0 |
| Streptococcus (Strc493) | 4 | 2 | 8 | 7 | 13 | 5 | 6 | 7 |
| Streptococcus pyogenes (Strpyo) | 1 | 0 | 0 | 0 | 3 | 0 | 2 | 2 |
| Staphylococcus aureus (Staaur) | 3 | 1 | 0 | 0 | 0 | 0 | 2 | 3 |
| Lactobacillus and Enterococcus (Lab) | 3 | 0 | 4 | 2 | 7 | 0 | 0 | 1 |
| Clostridium coccoides—Eubacterium rectale group (EREC) | 2 | 0 | 5 | 2 | 5 | 0 | 2 | 1 |
| Listeria, Brochothrix (Lis 637,1255) | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 1 |
| Ruminococcus bromii, Ruminococcus flavefaciens (Rbro, Rfla) | 0 | 0 | 1 | 1 | 3 | 0 | 0 | 0 |
| Veillonella group incl. Veillonella parvula (Veil,Vepa) | 1 | 0 | 2 | 1 | 5 | 0 | 4 | 3 |
| Bacteroides/Prevotella group (Bac303) | 4 | 2 | 7 | 2 | 4 | 1 | 4 | 3 |
| Cytophaga‐Flavobacteria (CF 319) | 2 | 1 | 2 | 1 | 8 | 3 | 4 | 4 |
| Prevotella intermedia (Prin) | 1 | 0 | 4 | 1 | 2 | 0 | 0 | 0 |
| Burkholderia (Burcep, Burkho) | 0 | 0 | 5 | 3 | 4 | 2 | 0 | 1 |
| Pseudomonas (Ps, Pseaer A, Pseaer B) | 2 | 1 | 5 | 5 | 4 | 0 | 3 | 4 |
A, adenoids; T, tonsils