Table 2 Frequencies of aberrant methylation of death‐associated protein kinase, p16, SHP1, E‐cadherin and oestrogen receptor genes.
| MGUS | MM (%) | p Value | |
|---|---|---|---|
| n | 19 | 32 | |
| DAP kinase | |||
| M | 6 (31.6) | 18 (56.3) | 0.146 |
| U | 13 (68.4) | 14 (43.7) | |
| p16 | |||
| M | 1 (5.3) | 17 (53.1) | 0.001 |
| U | 18 (94.7) | 15 (46.9) | |
| SHP1 | |||
| M | 6 (31.6) | 27 (84.4) | <0.001 |
| U | 13 (68.4) | 5 (15.6) | |
| ECAD | |||
| M | 0 (0) | 18 (56.3) | <0.001 |
| U | 19 (100) | 14 (43.7) | |
| ER | |||
| M | 3 (15.8) | 13 (40.6) | 0.117 |
| U | 16 (84.2) | 19 (59.3) |
DAP, death‐associated protein gene; ECAD, E‐cadherin gene; ER, oestrogen receptor gene; M, methylated gene status; MGUS, monoclonal gammopathy of undetermined significance; MM, multiple myeloma; SHP1, suppressor of high‐copy PP1 gene; U, unmethylated gene status.
M and U values are n (%).