Table 1 Demographic, biochemical, and study characteristics of the two groups.
| All subjects | Women | Men | ||||
|---|---|---|---|---|---|---|
| High TG (n = 46) | Control (n = 46) | High TG (n = 22) | Control (n = 27) | High TG (n = 24) | Control (n = 19) | |
| Age (years) | 41.4 (6.9) | 40.9 (8.4) | 41.8 (6.7) | 40.1 (8.2) | 41.0 (7.1) | 42.2 (8.6) |
| Body mass index (kg/m2) | 27.1 (2.6) | 26.0 (2.9) | 27.6 (2.6) | 26.1 (2.8) | 26.6 (2.5) | 25.8 (2.6) |
| Total cholesterol (mmol/l) | 4.68 (0.42) | 4.73 (0.48) | 4.69 (0.50) | 4.75 (0.36) | 4.67 (0.33) | 4.69 (0.65) |
| HDL cholesterol (mmol/l) | 1.05 (0.26)** | 1.34 (0.30) | 1.08 (0.30)** | 1.40 (0.24) | 1.04 (0.22) | 1.24 (0.38) |
| LDL cholesterol (mmol/l) | 2.95 (0.58) | 2.95 (0.41) | 2.99 (0.62) | 2.97 (0.36) | 2.91 (0.56) | 2.92 (0.49) |
| TG (mmol/l) | 2.22 (0.36)** | 0.95 (0.26) | 2.16 (0.35)** | 0.90 (0.22) | 2.28 (0.37)** | 1.05 (0.29) |
| Glucose (mmol/l) | 5.04 (0.47) | 5.14 (0.37) | 90.5 (9.3) | 93.7 (7.2) | 5.10 (0.43) | 5.11 (0.35) |
| Haemoglobin (g/l) | 142 (12) | 141 (12) | 134 (9) | 134 (10) | 149 (9) | 151 (5) |
| hsCRP (mg/l) | 2.4 (1.7) | 2.0 (1.6) | 3.0 (1.9) | 2.2 (1.7) | 1.8 (1.3) | 1.7 (1.3) |
| LVEF (%) | 67.7 (3.3) | 69.0 (3.3) | 67.7 (3.3) | 69.0 (3.3) | 67.9 (3.3) | 68.2 (2.9) |
| LVMI (g/m2) | 87.6 (16.9) | 85.0 (17.0) | 87.6 (16.9) | 85.0 (17.0) | 91.1 (18.7) | 92.3 (13.8) |
| Mitral E:A | 1.25 (0.12) | 1.28 (0.13) | 1.19 (0.09) | 1.22 (0.08) | 1.26 (0.11) | 1.37 (0.11) |
| Baseline HR (beats/min) | 76.2 (10.1) | 72.6 (10.1) | 78.8 (11.4) | 76.5 (12.10 | 72.3 (9.0) | 67.2 (5.5) |
| Baseline SBP (mm Hg) | 126.4 (14.3) | 125.4 (16.8) | 127.0 (13.8) | 125.6 (15.5) | 125.9 (15.0) | 125.0 (19.4) |
| Baseline DBP (mm Hg) | 74.2 (10.1) | 75.0 (8.4) | 78.2 (7.3) | 78.5 (5.9) | 78.3 (6.5) | 80.0 (11.6) |
| Peak HR (beats/min) | 97.6 (14.0) | 95.4 (14.1) | 97.6 (14.0) | 95.4 (14.1) | 92.7 (12.5) | 88.3 (11.3) |
| Peak SBP (mm Hg) | 127.8 (15.8) | 127.0 (13.7) | 127.8 (15.8) | 127.0 (13.7) | 124.8 (13.4) | 128.6 (5.6) |
| Peak DBP (mm Hg) | 78.4 (5.8) | 77.5 (7.6) | 78.4 (5.8) | 77.5 (7.6) | 80.0 (8.5) | 82.1 (11.2) |
| Baseline DPFV (cm/s) | 24.0 (2.6) | 23.9 (4.1) | 24.5 (2.5) | 23.9 (3.7) | 23.5 (2.8) | 24.0 (4.8) |
| Hyperaemic DPFV (cm/s) | 66.2 (14.7)* | 72.8 (17.2) | 67.5 (13.0) | 75.4 (16.6) | 64.9 (16.3) | 69.3 (17.8) |
| Coronary flow reserve | 2.76 (0.60)* | 3.06 (0.65) | 2.76 (0.49)* | 3.17 (0.65) | 2.77 (0.71) | 2.90 (0.61) |
| Carotid IMT (mm) | 0.54 (0.10)* | 0.49 (0.10) | 0.55 (0.10)** | 0.46 (0.09) | 0.53 (0.10) | 0.54 (0.10) |
*p<0.05 versus control; **p<0.01 versus control.
DBP, diastolic blood pressure; DPFV, diastolic mean peak flow velocity; HDL, high density lipoprotein; HR, heart rate; hsCRP, high sensitive C reactive protein; IMT, intima–media thickness; LDL, low density lipoprotein; LVEF, left ventricular ejection fraction; LVMI, left ventricular mass index; SBP, systolic blood pressure; TG, triglyceride.