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. 2006 May;92(5):712–718. doi: 10.1136/hrt.2005.062950

Table 1 Determinants of diastolic function.

• Myocardial relaxation
- load
- inactivation (calcium homeostasis, myofilaments, energetics)
- non‐uniformity
• Passive properties of ventricular wall
- myocardial stiffness (cytoskeleton, extracellular matrix)
- wall thickness
- chamber geometry
• Other determinants
- structures surrounding the ventricle (pericardium, lungs, remaining cardiac chambers)
- left atrium, pulmonary veins and mitral valve
- heart rate