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. 2006 Jan;92(1):85–89. doi: 10.1136/hrt.2004.049502

Table 2 Outcome of TPG before and after treatment with prostacyclin in five patients.

1 2 3 4 5 Mean (SD) p Value*
Duration of treatment before repeat catheterisation (days) 51 49 36 78 75 58 (18)
Before long term prostacyclin treatment
 At catheterisation baseline
  Mean PA pressure (mm Hg) 61 66 36 41 50 51 (12.7)
  Mean LA pressure (mm Hg) 33 24 21 18 22 24 (5.7)
  TPG (mm Hg) 28 42 15 23 28 27 (9.8)
  CI (l/min/m2) 1.7 5.5 1.9 1.6
 With acute vasodilator testing
  Mean PA pressure (mm Hg) 43 58 31 34 42 42 (10.5)
  Mean LA pressure (mm Hg) 33 28 15 16 23 23 (7.7)
  TPG (mm Hg) 11 30 16 18 19 19 (6.8)
  CI (l/min/m2) 2.3 5.5† 1.9 1.6
During long term prostacyclin treatment
 At catheterisation baseline
  Mean PA pressure (mm Hg) 48 50 29 34 42 41 (9.0) <0.01
  Mean LA pressure (mm Hg) 31 25 20 17 20 23 (5.5) 0.14
  TPG (mm Hg) 17 25 9 17 22 17 (6.7) 0.01
  CI (l/min/m2) 3.5 2.6 1.2 1.6
 With acute vasodilator testing
  Mean PA pressure (mm Hg) 44 38 26 33 38 35.8 (6.7) 0.19
  Mean LA pressure (mm Hg) 43 22 19 20 17 24.2 (10.7) 0.722
  TPG (mm Hg) 2 16 7 13 21 11 (7.5) <0.05
  CI (l/min/m2) 4.7 2.8 1.2 1.5

Data are mean (SD).

*Before versus during treatment with prostacyclin.

LA, left atrial; PA, pulmonary artery.

Where LA pressure is stated this may also have been determined by pulmonary capillary wedge pressure assessment.