Skip to main content
. 2000 May 23;97(12):6379–6384. doi: 10.1073/pnas.120166297

Figure 4.

Figure 4

SRC-3−/− females have delayed vaginal opening and low levels of E2. (A) Vaginal opening time. Individual distribution and average vaginal opening time are indicated for SRC-3+/+, SRC-3+/−, and SRC-3−/− females. There are statistical differences (P < 0.001) between SRC-3−/− and SRC-3+/+/SRC-3+/− mice. (B) Serum E2 concentrations in control and knockout females. Control mice include wild-type and SRC-3+/− mice. The E2 values are presented as average ± SD (n = 8). E2 levels in knockout mice are statistically lower than those in control mice at all ages assayed (P < 0.01, t test).