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. 2006 Jan 6;92(8):1047–1054. doi: 10.1136/hrt.2005.069419

Table 4 Pharmacological treatment of both men and women with angina for the year ending March 2002.

Treatment Age group (years) p Value for trend for age groups
<45 45–54 55–64 65–74 75–84 ⩾85 <75 ⩾75 All ages
Number 206 930 2 278 3 167 2 355 572 6581 2 927 9508
β blocker 95 (46.1%) 505 (54.3%) 1 235 (54.2%) 1 585 (50.0%) 1 035 (43.9%) 195 (34.1%) 3 420 (52.0%) 1 230 (42.0%) 4650 (48.9%) <0.001
CCB 46 (22.3%) 342 (36.8%) 1 010 (44.3%) 1 385 (43.7%) 1 050 (44.6%) 207 (36.2%) 2 783 (42.3%) 1 257 (42.9%) 4040 (42.5%) <0.001
Nitrates 90 (43.7%) 464 (49.9%) 1 219 (53.5%) 1 751 (55.3%) 1 441 (61.2%) 338 (59.1%) 3 524 (53.5%) 1 779 (60.8%) 5303 (55.8%) <0.001
Nicorandil 1 (0.5%) 6 (0.6%) 33 (1.4%) 28 (0.9%) 43 (1.8%) 11 (1.9%) 68 (1.0%) 54 (1.8%) 122 (1.3%) 0.002
ACEI 42 (20.4%) 246 (26.5%) 686 (30.1%) 1 016 (32.1%) 743 (31.5%) 137 (24.0%) 1 990 (30.2%) 880 (30.1%) 2870 (30.2%) <0.001
ARB 3 (1.5%) 24 (2.6%) 75 (3.3%) 168 (5.3%) 96 (4.1%) 18 (3.1%) 270 (4.1%) 114 (3.9%) 384 (4.0%) <0.001
ACEI/ARB 43 (20.9%) 264 (28.4%) 735 (32.3%) 1 138 (35.9%) 815 (34.6%) 150 (26.2%) 2 180 (33.1%) 965 (33.0%) 3145 (33.1%) <0.001
Statins 79 (38.3%) 523 (56.2%) 1 353 (59.4%) 1 864 (58.9%) 848 (36.0%) 53 (9.3%) 3 819 (58.0%) 901 (30.8%) 4720 (49.6%) <0.001
Aspirin 104 (50.5%) 546 (58.7%) 1 592 (69.9%) 24 05 (75.9%) 1 698 (72.1%) 375 (65.6%) 4 647 (70.6%) 2 073 (70.8%) 6720 (70.7%) <0.001
Clopidogrel 7 (3.4%) 40 (4.3%) 88 (3.9%) 140 (4.4%) 89 (3.8%) 15 (2.6%) 275 (4.2%) 1 04 (3.65%) 379 (4.0%) 0.332
Antiplatelets* 105 (51.0%) 567 (61.0%) 1 636 (71.8%) 2 483 (78.4%) 1 149 (74.3%) 383 (67.0%) 4 791 (72.8%) 2 132 (72.8%) 6923 (72.8%) <0.001
Warfarin 3 1.5%) 25 (2.7%) 93 (4.1%) 176 (5.6%) 205 (8.7%) 25 (4.4%) 297 (4.5%) 230 (7.9%) 527 (5.5%) <0.001
Optimal treatment† 25 (12.1%) 166 (17.8%) 450 (19.8%) 621 (19.6%) 325 (13.8%) 23 (4.0%) 1 262 (19.2%) 348 (11.9%) 1610 (16.9%) <0.001

*Aspirin or clopidogrel; †antiplatelet agent + statin + angiotensin converting enzyme inhibitor (ACEI).

ARB, angiotensin receptor blocker; CCB, calcium channel blocker.