Table 3 Proportion of patients admitted to hospital for a cardiovascular cause (principal discharge diagnosis) over 20 years, according to the presence of angina and ischaemic change on electrocardiogram at baseline.
Men | Women | |||||||
---|---|---|---|---|---|---|---|---|
No angina, no ischaemic changes on ECG (n = 5834) | No angina, ischaemic changes on ECG (n = 545) | Angina, no ischaemic changes on ECG (n = 517) | Angina, ischaemic changes on ECG (n = 152) | No angina, no ischaemic changes on ECG (n = 6961) | No angina, ischaemic changes on ECG (n = 594) | Angina, no ischaemic changes on ECG (n = 681) | Angina, ischaemic changes on ECG (n = 118) | |
Any cardiovascular cause | 1859 (31.9) | 230 (42.2)*** | 219 (42.4)*** | 72 (47.4)*** | 1647 (23.7) | 211 (35.5)*** | 237 (34.8)*** | 62 (52.5)*** |
1.00 | 1.57 (1.37 to 1.81) | 1.40 (1.21 to 1.62) | 2.40 (1.88 to 3.07) | 1.00 | 1.45 (1.25 to 1.68) | 1.38 (1.20 to 1.59) | 2.54 (1.96 to 3.29) | |
Coronary heart disease | 821 (14.1) | 113 (20.7)*** | 117 (22.6)*** | 37 (24.3)*** | 557 (8.0) | 83 (14.0)*** | 110 (16.2)*** | 24 (20.3)*** |
1.00 | 1.78 (1.46 to 2.18) | 1.72 (1.40 to 2.10) | 2.51 (1.77 to 3.54) | 1.00 | 1.65 (1.30 to 2.09) | 1.76 (1.42 to 2.18) | 2.13 (1.40 to 3.26) | |
Myocardial infarction | 652 (11.2) | 79 (14.5)* | 86 (16.6)*** | 32 (21.1)*** | 393 (5.6) | 61 (10.3)*** | 78 (11.5)*** | 18 (15.4)*** |
1.00 | 1.50 (1.18 to 1.91) | 1.57 (1.24 to 1.98) | 2.79 (1.92 to 4.06) | 1.00 | 1.66 (1.67 to 2.19) | 1.78 (1.89 to 2.29) | 2.36 (1.45 to 3.85) | |
Heart failure | 227 (3.9) | 40 (7.3)*** | 33 (6.4)** | 15 (9.9)*** | 177 (2.5) | 51 (8.6)*** | 47 (6.9)*** | 13 (11.0)*** |
1.00 | 2.01 (1.42 to 2.83) | 1.34 (0.92 to 1.96) | 3.48 (2.03 to 5.98) | 1.00 | 2.80 (2.03 to 3.87) | 2.11 (1.51 to 3.00) | 3.89 (2.18 to 6.94) | |
Atrial fibrillation | 60 (1.0) | 7 (1.3) | 12 (2.3)** | 0 (0) | 65 (0.9) | 11 (1.9)* | 20 (2.9)*** | 1 (0.8) |
1.00 | 1.51 (0.68 to 3.34) | 2.24 (1.15 to 4.34) | — | 1.00 | 1.92 (0.99 to 3.69) | 2.92 (1.73 to 4.92) | 1.00 (0.14 to 7.33) | |
Stroke | 371 (6.4) | 54 (9.9)** | 35 (6.8) | 12 (7.9) | 423 (6.1) | 59 (9.9)*** | 61 (9.0)** | 14 (11.9)* |
1.00 | 1.57 (1.17 to 2.10) | 0.93 (0.65 to 1.33) | 1.75 (0.97 to 3.14) | 1.00 | 1.27 (0.95 to 1.69) | 1.30 (0.98 to 1.71) | 1.87 (1.08 to 3.22) | |
Aortic aneurysm | 54 (0.9) | 6 (1.1) | 4 (0.8) | 4 (2.6) | 13 (0.2) | 0 (0) | 1 (0.1) | 1 (0.8) |
1.00 | 1.33 (0.56 to 3.14) | 0.76 (0.27 to 2.17) | 4.67 (1.60 to 13.57) | 1.00 | — | 0.71 (0.09 to 5.47) | 5.45 (0.67 to 44.30) | |
Venous thromboembolism | 102 (1.7) | 10 (1.8) | 9 (1.7) | 2 (1.3) | 72 (1.0) | 6 (1.0) | 10 (1.5) | 1 (0.8) |
1.00 | 1.33 (0.69 to 2.58) | 1.08 (0.54 to 2.18) | 1.40 (0.34 to 5.78) | 1.00 | 0.98 (0.42 to 2.27) | 1.12(0.56 to 2.21) | 0.76 (0.10 to 5.59) |
ECG, electrocardiogram.
Values are n (%) or adjusted HR (95% CI).
*p<0.05; **p<0.01; ***p<0.001 for the proportion of hospitalisations in each group compared with the group with no angina and no ischaemic change on ECG.