Table 4 Relationship of plasma von Willebrand factor and soluble P‐selectin levels with quartiles of systolic, diastolic and pulse pressure (n = 664).
| Systolic blood pressure | 1st Quartile (<122 mm Hg) | 2nd Quartile (⩾122 and <136 mm Hg) | 3rd Quartile (⩾136 & <150 mm Hg) | 4th Quartile (⩾150 mm Hg) | P value |
|---|---|---|---|---|---|
| Number of patients (n) | 187 | 162 | 177 | 138 | |
| Age, mean (SD), years | 65.40 (10.15) | 69.19 (8.96) | 68.66 (8.23) | 70.36 (7.06) | <0.001 |
| Male (%) | 142 (75.9) | 128 (79) | 119 (67.6) | 87 (63) | 0.006 |
| Body mass index, mean (SD), kg/m2 | 27.66 (6.31) | 28.17 (5.16) | 28.61 (5.88) | 27.82 (5.05) | 0.431 |
| Serum cholesterol, mean (SD), mmol/l | 5.19 (1.02) | 5.09 (0.89) | 5.19 (0.96) | 5.31 (1.03) | 0.297 |
| vWf (IQR), IU/dl | 142 (117–160) | 142 (127–160) | 145 (125–166) | 139 (122–160) | 0.564 |
| Soluble P‐selectin (IQR), ng/ml | 32 (26–40) | 31 (24–40) | 33 (25–41) | 31 (24–40) | 0.621 |
| Diastolic blood pressure | 1st Quartile (<70 mm Hg) | 2nd Quartile (⩾70 and <80 mm Hg) | 3rd Quartile (⩾80 and <84 mm Hg) | 4th Quartile (⩾84 mm Hg) | p Value |
|---|---|---|---|---|---|
| Number of patients (n) | 97 | 202 | 171 | 194 | |
| Age, mean (SD) years | 69.86 (9.54) | 68.29 (9.20) | 68.21 (8.98) | 67.36 (8.32) | 0.167 |
| Male (%) | 65 (67.7) | 139 (68.8) | 125 (73.1) | 147 (75.8) | 0.342 |
| Body mass index, mean (SD) kg/m2 | 27.23 (5.04) | 28.20 (6.38) | 27.70 (5.5) | 28.68 (5.28) | 0.150 |
| Serum cholesterol, mean (SD) mmol/l | 5.15 (1.04) | 5.09 (0.96) | 5.22 (0.92) | 5.29 (1) | 0.223 |
| vWf (IQR) IU/dl | 142 (125–171) | 144 (120–158) | 138 (121–159) | 142 (125–163) | 0.436 |
| Soluble P‐selectin (IQR) ng/ml | 31 (26–40) | 31 (25–40) | 33 (25–41) | 33 (24–41) | 0.884 |
| Pulse pressure | 1st Quartile (<46 mm Hg) | 2nd Quartile (⩾46 and <56 mm Hg) | 3rd Quartile (⩾56 and <70 mm Hg) | 4th Quartile (⩾70 mm Hg) | p Value |
|---|---|---|---|---|---|
| Number of patients (n) | 183 | 167 | 181 | 133 | |
| Age, mean (SD), years | 64.80 (9.65) | 68.16 (9.54) | 69.19 (7.88) | 71.71 (6.71) | <0.001 |
| Male (%) | 148 (80.9) | 125 (74.9) | 128 (71.1) | 75 (56.4) | <0.001 |
| Body mass index, mean (SD), kg/m2 | 28.03 (6.24) | 28.38 (5.63) | 28.36 (5.26) | 27.34 (5.44) | 0.381 |
| Serum cholesterol, mean (SD), mmol/l | 5.09 (0.94) | 5.18 (1) | 5.29 (0.97) | 5.19 (1.01) | 0.334 |
| vWf (IQR), IU/dl | 141 (115–160) | 142 (126–166) | 142 (124–158) | 142 (124–167) | 0.500 |
| Soluble P‐selectin (IQR), ng/ml | 34 (26–41) | 31 (24–40) | 32 (25–41) | 31 (24–40) | 0.370 |
IQR, interquartile range; vWf, von Willebrand factor.