Table 1 Haemodynamic, coronary blood flow and wall thickening results (mean (1SD)).
| Baseline (n = 12) | Moderate stenosis (n = 8) | Severe stenosis (n = 12) | p Value (ANOVA) | |
|---|---|---|---|---|
| Heart rate (bpm) | 128 (9) | 126 (6) | 126 (7) | 0.88 |
| Mean AoP (mm Hg) | 114 (10) | 112 (10) | 112 (11) | 0.82 |
| Mean CAP (mm Hg) | 114 (10) | 90 (10) | 78 (12) | <0.001 |
| Mean trans‐stenotic gradient (mm Hg) | 1 (1) | 22 (2) | 34 (4) | <0.001 |
| LAD CBF (ml/min) | 19.5 (5.8) | 15.5 (5.5) | 13.5 (4.8) | 0.18 |
| LCx CBF (ml/min) | 22.7 (3.7) | 26.7 (5.1) | 27.5 (4.6) | 0.16 |
| Total CBF to LAD bed (ml/min) | 19.5 (5.8) | 19.5 (5.8)* | 18.5 (4)* | 0.93 |
| % WT LAD bed (non‐collataralised zone) | 32.7 (1.4) | 32.6 (1.3) | 32.6 (1.5) | 0.95 |
| % WT LAD bed (collateralised zone) | 33.0 (1.8) | 32.6 (1.4) | 32.6 (1.4) | 0.84 |
| %WT LCx bed | 32.2 (0.3) | 32.3 (0.7) | 31.9 (0.5) | 0.78 |
ANOVA, analysis of variance; AoP, aortic pressure; CAP, coronary artery pressure; CBF, coronary blood flow; LAD, left anterior descending coronary artery; LCx, left circumflex coronary artery; WT, wall thickening.
*Derived by adding LAD CBF to the increase in LCx CBF.