Table 2 CIN in the EU and annual estimates of the number of women with overtreatment.

	EU
Number of inhabitants (2005)	375 million
Number of cases of CIN1, CIN2 and CIN3 in the EU	330 000
Number of CIN2 cases in the EU	82 500
Annual number of overtreated patients with CIN2 in the EU by CIN grade	66 000
Annual number of overtreated patients with CIN2 in the EU by Q‐Ki‐67	57 750
Annual number of overtreated patients with CIN2 in the EU by Q‐Ki‐67 and pRb	47 025
Improvement because of Q‐Ki‐67 per year	8 250
Improvement because of Q‐Ki‐67 and pRb per year	18 975

CIN, cervical intraepithelial neoplasia; EU, European Union; pRb, retinoblastoma protein.

Data modified from Baak et al. Cell Oncol 2005;27:277–80.