Effect of [Ca2+] at bundle tip, CSS. As the [Ca2+] at the bundle tip when the channel is open, CSS, increases from 8 to 35 μM, the speed of fast adaptation increases. Unlike the adaptation speed, the magnitudes of responses were minimally affected by CSS. At F = 50 pN, the response decay was fit with an exponential curve (dashed line). The time constants were 0.9, 0.6, and 0.3 ms from left to right.