Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
ITC-derived thermodynamic parameters for the 27-mer quadruplex construct binding TMPyP4 in variable salt conditions at 25°C (298 K)
| [KCl] (mM) | K1 (M−1) × 10−6 | ΔG1 (kcal/mol) | K2 (M−1) × 10−5 | ΔG2 (kcal/mol) |
|---|---|---|---|---|
| 20 | 43 (±3) | −10.4 | 18 (±0.6) | −8.5 |
| 50 | 25 (±2) | −10.1 | 7.0 (±0.2) | −8.0 |
| 100 | 5.4 (±.5) | −9.2 | 2.0 (±0.1) | −7.3 |
| 200 | 11 (±1) | −9.6 | 2.3 (±0.1) | −7.3 |
Parameters are for the two-independent-sites binding model. The uncertainties listed for ΔHi were determined by Monte Carlo analysis.
