TABLE 1.
35 μM | Steady-state [Ca2+] at the binding site when channel stays open | |
FR | 25.0 pN | Resting tension |
ΔF | 1.5 pN | Channel gating threshold |
δ | 5 nm | Gating swing |
Fcrit | 24 pN | Critical tension above which open channels remain open regardless of [Ca2+] |
α | 0.1 μM−1 ms−1 | Ca2+-binding rate to the fast adaptation modulator |
k2 | 0.25 ms−1 | Ca2+-dissociation rate from the fast adaptation modulator |