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. 2006 Dec 22;92(6):1938–1951. doi: 10.1529/biophysj.106.093500

FIGURE 2.

FIGURE 2

Resurgent Na current in wild-type and med neurons. (A) Voltage protocol to elicit resurgent current and representative traces from Purkinje and cerebellar nuclear cells. Currents are normalized to the peak of the transient Na current elicited by a step to 0 mV. (B, left and center bar groups) Average transient (0 mV) and resurgent current (−30 mV) amplitudes from PKJ wild-type (WT) (N = 78), PKJ med (N = 19), CBN WT (N = 48), and CBN med (N = 8) neurons (left axis). Note that transient current is divided by 10, for an axis range of 0–15 nA, whereas the resurgent-current amplitude range is 0–1.5 nA. (B, right bar group) Resurgent current normalized to the transient current at 0 mV (right axis).