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The F172S mutant can mediate IFNγ-induced gene expression. (A). Expression of WT Stat1 and the F172S mutant in U3A cells. WCL were subjected to immunoblot analysis with anti-Stat1 Ab. (B) IFNγ-induced IRF-1 expression in Stat1-reconstituted U3A cells. WCL were subjected to immunoblot blot analysis with anti-IRF-1 Ab.
