Table 1.
Other Age-Dependent Traits of Parental Mouse Strains SAMP6 and AKR/J. Significance levels are based on a stringent two-tailed Fisher-Behrens t-test (for samples of unequal or unknown variance), comparing AKR/J to SAMP6 values.
| Males | Total Weight (g) ± SD | Spine Area (cm2) ± SD | Global Bone Area (cm2) ± SD | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Age (mo) | AKR/J | SAMP6 | P< | AKR/J | SAMP6 | P< | AKR/J | SAMP6 | P< |
| 3.0 - 3.2 | 29.0±2.0 | 36.0±2.6 | 10-3 | 5.19±0.12 | 5.47±0.15 | 10-3 | 9.11±0.53 | 10.4±0.57 | 10-3 |
| 4.0 - 4.4 | 30.7±3.1 | 36.3±10 | 0.05 | 5.41±0.11 | 5.45±0.25 | NS | 9.50±0.69 | 10.5±1.1 | 10-2 |
| 6.0-6.1 | 33.7±4.1 | 39.0±6.4 | 0.02 | 5.56±0.13 | 5.54±0.32 | NS | 10.1±0.76 | 11.2±1.5 | 0.03 |
| 8.2-8.4 | 35.4±5.2 | 39.0±4.3 | 0.07 | 5.57±0.29 | 5.54±0.17 | NS | 10.4±1.19 | 11.2±1.1 | 0.10 |
| Females | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Age (mo) | AKR/J | SAMP6 | P< | AKR/J | SAMP6 | P< | AKR/J | SAMP6 | P< |
| 3.1-3.2 | 25.3±1.2 | 33.5±1.7 | 10-3 | 5.01±0.15 | 5.19±0.12 | NS | 8.02±0.47 | 10.4±0.58 | 10-3 |
| 119-129 | 29.0±2.2 | 37.2±11 | 0.05 | 5.39±0.16 | 5.41±0.11 | NS | 9.33±0.72 | 11.3±0.60 | 10-3 |
| 179-192 | 32.5±3.1 | 39.2±2.0 | 10-3 | 5.46±0.13 | 5.56±0.13 | NS | 9.57±0.66 | 11.9±0.37 | 10-3 |
| 241-251 | 29.0±7.0 | 42.3±3.6 | 10-3 | 5.14±0.77 | 5.57±0.29 | NS | 8.66±2.36 | 12.4±0.87 | 10-3 |