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. 2002 May 1;16(9):1077–1088. doi: 10.1101/gad.979102

Figure 1.

Figure 1

Generation of Y4 receptor knockout mice. (A) Targeting vector design and screening strategy. Small arrows indicate the position and orientation of oligonucleotides used in the PCR analysis, and bars indicate the position of probes used for Southern analysis of genomic DNA from targeted ES cells as well as knockout animals. (B,C) Southern analysis of genomic DNA isolated from conditional and germ line Y4 receptor knockout mice cut with EcoRI or EcoRV, using probes A and B, respectively.