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Body weight of Y4−/−,ob/ob double knockout mice. Body weight of male Y4−/−,ob/ob (♦) compared with ob/ob (⋄), Y4−/−,ob/ob (▴), OB/ob (▵) and wild-type (□) mice. Values are means ± SEM of 20–32 mice per group. *P < 0.05 versus curve for ob/ob mice.
