Table 2.

Weight of white adipose tissue deposits, and plasma hormone and metabolite concentrations in male Y4^−/−,ob/ob double knockout mice and controls

	OB/ob	Y4−/−OB/ob	ob/ob	Y4−/−ob/ob
Sum of WAT (%)	2.48 ± 0.22	3.51 ± 0.33a	8.19 ± 0.29c	7.51 ± 0.30c
Insulin (pmol/L)	89 ± 16	201 ± 41	7420 ± 2230c	9800 ± 2300b
Glucose (mmol/L)	10.5 ± 0.5	12.8 ± 0.7	18.3 ± 4.0b	13.7 ± 2.0
PP (nmol/L)	ND	ND	1.18 ± 1.04	6.45 ± 1.70d

Data are means ± SEM of 6–18 mice per group. Sum of WAT, combined weight of right inguinal, right epididymal or pcriovarian, right retroperitoneal, and mesenteric white adipose tissue as a percent of body weight; PP, pancreatic polypeptide; ND, not determined. 

^aP < 0.05, ^bP < 0.01, ^cP < 0.001 versus OB/ob control mice. ^dP < 0.05 versus ob/ob mice.