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. Author manuscript; available in PMC: 2008 Apr 1.
Published in final edited form as: Dev Biol. 2006 Dec 21;304(1):272–285. doi: 10.1016/j.ydbio.2006.12.033

Figure 3.

Figure 3

Expression of ciliary body genes in transition zones.

In situ hybridization on e5 tissue. (A) Lamininβ1 is expressed in the presumptive ciliary body and not in the neural retina. (B,C) Lamininβ1 is expressed in the transition zone between induced neural retina and pigmented epithelium (arrows). (D) Nidogen is expressed in the presumptive ciliary body and not in the neural retina. (E,F) Nidogen expression is also seen in induced transition zones (arrow). (G,H) Thymosinβ4 is expressed throughout the optic tissue but in the ciliary body, expression is upregulated (asterisks). (I) Thymosinβ4 is upregulated in the transition zones compared to the endogenous neural retina (asterisks). (J) Wnt2b is specifically expressed at the tip of the optic cup and in the lens epithelium. (K,L) Induced transition zone in the same tissue section as J; wnt2b expression can not be identified. Abbreviations as in Fig 1. Scale: bar=50μm.