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. 2007 Feb 26;402(Pt 3):559–566. doi: 10.1042/BJ20061194

Figure 3. MOZ activates the GSTP promoter activity through the GPE.

Figure 3

(A) Diagram of the 5′-flanking region of the rat GSTP gene and the reporter constructs for observing the effect of MOZ on the promoter activity of the GSTP gene. (B) We co-transfected 100 ng of the reporter plasmid with (grey columns) or without (white columns) 1 μg of MOZ expression plasmid (pCI-MOZ) into H4IIE rat hepatoma cells. All transfection assays were repeated at least three times. The relative luciferase activity was calculated from mean values relative to the activity of −2.5GST-luciferase in the absence of MOZ. Each error bar indicates ±S.D. (C) Dose-dependent transactivation of −2.5GST-luciferase by MOZ. Relative luciferase activities are shown as in (B).