Figure 3. Percent bound endosomal ligand at the end of a 180 min incubation for a range of ligands, incubation concentrations and endosomal volumes of 4×10⁻¹⁵ litres/cell (light grey bars), 1×10⁻¹⁴ litres/cell (grey bars) and 2×10⁻¹³ litres/cell (black bars).

Simulation results are for internalization impaired receptors using the parameter estimates listed in Tables 1 and 2.