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. 2007 Jan 5;92(7):2403–2411. doi: 10.1529/biophysj.106.097964

FIGURE 1.

FIGURE 1

SGLT1 membrane topology and probe structures. (A) Chemical structures of tetramethylrhodamine-5-maleimide (TMR5M) and tetramethylrhodamine-6-maleimide (TMR6M) attached to a sulfur atom of a cysteine residue. (B) Cartoon illustrating a pseudo-three-dimensional membrane topology and the transmembrane segments around the disulfide bridge C255–C511 in SGLT1. TMS were schematically represented by cylinders and are identified by Roman numerals. The position of the disulfide bridge C255–C511 close to the membrane is shown as is the nearby residue Q457.