TABLE 5.
Temperature (°C)
|
||||
---|---|---|---|---|
22* | 30 | 35 | 40 | |
K0 (ml O2 cm−1 × min−1 . atm−1) × 10−5 | 2.52 | 3.08 | 4.18 | 4.81 |
P50 (mmHg)† | 0.55 | 1.21 | 1.98 | 3.23 |
DMb (cm2s−1) ×10−7 | 4.24 | 6.09 | 7.85 | 8.37 |
DMbCMb(cm2s−1 mM) × 10−7 myocardium‡ | 0.81 | 1.16 | 1.49 | 1.59 |
DMbCMb(cm2s−1 mM) × 10−7 skeletal muscle‡ | 1.79 | 2.56 | 3.29 | 3.54 |
Equipoise diffusion PO2 (mmHg) myocardium | 2.72 | 2.63 | 1.67 | 0.15 |
Equipoise diffusion PO2 (mmHg) skeletal muscle | 6.67 | 7.27 | 6.08 | 4.24 |
Actual temperature for K0 measurements: 23°C, 30°C, 34.2°C, 40.4°C (38).
P50 calculated from the equation P50 = e0.098T–2.748, where T is in °C (49). Experimentally determined P50 of 1.5 mmHg at ∼25°C and K0 = 2.52 × 10−5 ml O2 cm−1 × min−1 × atm−1 yields equipoise diffusion PO2 1.77 mmHg for myocardium and 5.72 for skeletal muscle (10,74).
Mb concentration in rat myocardium assumed as 0.19 mM and 0.42 mM in rat skeletal muscle (10).