Table 3.
Donor | Chol | TG | VLDL | LDL | HDL | WT | Spleen WT |
---|---|---|---|---|---|---|---|
B6 | 34.4 ± 2.0 | 3.45 ± 0.25 | 20.6 ± 2.3 | 18.7 ± 1.2 | 2.02 ± 0.13 | 21.9 ± 0.8 g | 0.06 ± 0.007 g |
Vα14tg | 39.4 ± 2.2 | 4.74 ± 0.41 | 19.6 ± 3.1 | 16.3 ± 0.9 | 1.86 ± 0.28 | 23.7 ± 0.6 g | 0.06 ± 0.004 g |
CD1d−/− | 45.0 ± 2.4* | 5.77 ± 1.01* | 25.5 ± 3.1 | 17.3 ± 0.5 | 2.22 ± 0.18 | 24.0 ± 0.7 g | 0.09 ± 0.014 g |
Fasting plasma total cholesterol and triglyceride levels measured at sacrifice after 12 weeks of WTD feeding. No differences were observed in plasma total cholesterol or triglyceride levels between groups after 4 or 8 weeks on WTD. Plasma lipoproteins from a subset of mice in each group were separated via FPLC and the amount of VLDL, LDL, and HDL cholesterol was calculated based on the percentage of total cholesterol carried in each peak. Data are mean ± SEM, lipid values reported in micromolar plasma.
P < 0.05 CD1d−/− versus B6.