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. 2007 Mar;170(3):1108–1120. doi: 10.2353/ajpath.2007.060960

Figure 7.

Figure 7

Trx2 reduces hypercholesterolemia-induced atherosclerotic progression in ApoE-deficient mice. WT, Trx2, ApoE-deficient (ApoE), and ApoE-deficient/Trx2 TG mice (ApoE/TG) (n = 10 for each group) were fed with a Western-type diet for 8 weeks. a: Serum cholesterol was measured enzymatically. b: Serum NO was measured as NOx for both nitrite and nitrate (Cayman). c: Whole aortas were harvested, opened longitudinally, and stained en face with Oil Red O. Percentage of lesion area was quantified in d. e: Paraffin sections from aortic arches (10 sections from each aorta) were stained with Oil Red O. Percentage of lesion area was quantified in f. Data are presented are mean ± SEM. *P < 0.05.