Table 1.

Demographic characteristics, clinical ratings, and neuropsychological test scores (mean ± standard deviation where appropriate). Statistical tests are Students 2-tailed t-tests, uncorrected for multiple comparisons, with calculated P values shown. Years since onset indicates years since estimated initial onset of symptoms, based on subject/informant’s reported age at symptom onset. Some test scores were not available for all subjects; sample N for each test is shown in parenthesis.

	Controls N = 7	MCI N = 5	AD N = 8 (1 poss, 7 prob)	P: Ctl v. MCI	P: Ctl v. AD
Gender	6 F, 1 M	4 F, 1 M	4 F, 4 M
Age (years)	72.6 ± 5.7	78.1 ± 9.4	78.2 ± 7.2	0.229	0.124
Range	65.2 – 80.6	67.2 – 89.3	69.0 – 90.7
Education (years)	15.8 ± 5.2	15.0 ± 2.4	15.3 ± 3.3	0.762	0.813
APOE4 carriers	3	1 (1 unknown)	5
Years since onset		4.3 ± 0.8	5.3 ± 2.4
Range		3.0 – 5.2	2.0 – 9.4
Folstein MMSE	29.7 ± 0.5 (6)	26.4 ± 1.5 (5)	17.3 ± 6.9 (7)	0.0008	0.0009
Mattis DRS-Memory	24.0 ± 1.1 (6)	15.8 ± 2.4 (5)	9.5 ± 3.9 (8)	0.00003	0.000001
AVLT-Total learning	47.6 ± 8.2 (7)	28.6 ± 2.7 (5)	19.0 ± 5.0 (5)	0.0006	0.00004
AVLT-Percent recall	82.7 ± 22.4 (7)	13.2 ± 8.2 (5)	12.8 ± 21.7 (5)	0.00006	0.0003