Table 5.
Mean IQ values and associations by SNP and genotype
| Mean FSIQ (SD) | ||||
| Non-carriers | Carriers | Z-statistic | Adjusted p-value | |
| rs 2619539 | 91.02 (16.02) | 94.52 (15.92) | 1.02 | 0.308 |
| rs 3213207 | 94.16 (15.96) | 91.30 (16.06) | -1.60 | 0.109 |
| rs 1011313 | 93.50 (16.37) | 93.29 (13.23) | 1.29 | 0.198 |
| rs 2619528 | 96.36 (15.21) | 89.95 (16.30) | -1.65 | 0.098 |
| rs 760761 | 96.79 (15.18) | 88.77 (16.02) | -2.23 | 0.026 |
| rs 2619522 | 96.74 (15.29) | 89.23 (15.97) | -2.25 | 0.025 |
| rs 2619538 | 88.52 (16.57) | 95.04 (15.54) | 2.08 | 0.038 |
Observed mean FSIQ values of the total population (patients, siblings and controls) with standard deviation (SD) are given in 'carriers' versus the 'non-carriers' in which 'carriers' represent the carriers of the low-frequency allele. P-values are given for the comparison of FSIQ values between genotype groups (carriers and non-carriers) using ANOVA with GEE adjusting for age, gender, ethnicity, family membership, and educational level.